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贵州省黔东南州侗族成年人脂肪肝流行现况及其影响因素分析(PDF)

《现代预防医学》[ISSN:1003-8507/CN:51-1365/R]

期数:
2020年10期
页码:
1742-1745
栏目:
流行病与统计方法
出版日期:
2020-05-30

文章信息/Info

Title:
Prevalence and Influencing Factors of Fatty Liver among Adults with Dong Nationality in Qiandongnan Prefecture of Guizhou Province
作者:
朱海建1洪峰1关菡1张燕1王子云1唐学杰2尹朝辉3雷娟4袁薇5杨敬源1
1.贵州医科大学公共卫生学院,环境污染与疾病监控教育部重点实验室,贵阳,550025;
2.贵州医科大学大学城医院,贵阳,550025;
3.贵州医科大学第二附属医院,凯里,556000;
4. 贵阳市疾病预防控制中心,贵阳,550002;
5.贵贵州省疾病预防控制中心,贵阳,550004
Author(s):
ZHU Hai-jian* HONG Feng GUAN Han ZHANG Yan WANG Zi-yun TANG Xue-jie YIN Chao-hui LEI Juan YUAN Wei YANG Jing-yuan
*School of Public Health, Key Laboratory of Environmental Pollution Monitorning and Disease Control, Ministry of Education, Guizhou Medical University, Guiyang, Guizhou 550025, China
关键词:
侗族、脂肪肝、影响因素
Keywords:
Dong Nationality Fatty liver Influencing factors
分类号:
R181.3
DOI:
-
文献标识码:
A
摘要:
目的 调查贵州省黔东南州侗族成年人脂肪肝流行情况及其影响因素,为黔东南州侗族人群脂肪肝的预防提供依据。方法 采用多级抽样方法,对黔东南州侗族聚居地30~79岁人群进行问卷调查和体格检查,分析该地区脂肪肝的患病率及影响因素。结果 本次调查侗族成年人共计4 828人,其中脂肪肝患者804人(16.653%)。单因素分析结果显示,不同年龄、是否肥胖和血脂异常人群的脂肪肝患病率存在差异;非条件logistic回归分析显示,肥胖、高血压和血脂异常与黔东南州侗族人群脂肪肝患病存在关联;进一步联合分析显示,与无肥胖、无高血压、TG、LDL - C和HDL - C正常人群相比,“任意1项为阳性”、“任意2项为阳性”、“任意3项为阳性”、“任意4项或以上为阳性”的调整OR(95%CI)分别为2.845(2.201~3.678)、7.937(6.149~10.244)、14.994(11.128~20.204)、72.747(37.905~139.616),存在剂量效应关系(P for trend<0.05)。结论 黔东南州侗族人群脂肪肝患病率较高。肥胖、高血压、血脂异常是导致脂肪肝患病风险增加的重要因素。
Abstract:
Objective The study aimed to investigate the prevalence and influencing factors of fatty liver in Dong nationality adults in Qiandongnan Prefecture of Guizhou Province, and to provide basis for prevention of fatty liver in Dong nationality.Methods Using multi-level sampling method, the prevalence of fatty liver and its influencing factors were analyzed by questionnaire and physical examination among 30-79 year old population in Dong community in Qiandongnan Prefecture.Results There were 4828 Dong adults in this survey, including 804 fatty liver patients(16.653%). The results of single factor analysis showed that the prevalence of fatty liver was different in different age, obesity status and dyslipidemia groups;unconditional Logistic regression analysis showed that obesity, hypertension and dyslipidemia were associated with fatty liver disease among Dong people in Qiandongnan Prefecture. Further united analysis showed that compared with population without obesity, hypertension, normal of TG, LDL-C and HDL-C, the adjusted OR(95% CI) of those with “any one is positive”, “any two is positive”, “any three is positive”, “any 4 or more items are positive" were 2.845(2.201-3.678), 7.937(6.149-10.244), 14.994(11.128-20.204) and 72.747(37.905-139.616, which was dose effect relationship(P for trend<0.05).Conclusion The prevalence of fatty liver is high among Dong Nationality in Qiandongnan Prefecture. Obesity, hypertension and dyslipidemia are the important factors leading to the increased risk of fatty liver disease.

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备注/Memo

备注/Memo:
基金项目:“贵州省苗族、侗族、布依族世居自然人群环境暴露与健康风险的前瞻性队列研究”(黔科合平台人才[2018]5403)
作者简介:朱海建(1995 - ),男,硕士在读,研究方向:慢性病防治
通讯作者:杨敬源,E - mail:yang8880@sina.com
更新日期/Last Update: 2020-06-03