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马鞍山市肺癌筛查队列肺结节转归及影响因素研究(PDF)

《现代预防医学》[ISSN:1003-8507/CN:51-1365/R]

期数:
2022年14期
页码:
2517-2522
栏目:
流行病与统计方法
出版日期:
2022-07-30

文章信息/Info

Title:
Study on pulmonary nodules outcome and risk factors of lung cancer screening population in Ma’anshan
作者:
朱金亮1秦其荣12刘孟钰1何家镠1胡明军1黄芬1
1. 安徽医科大学公共卫生学院流行病与卫生统计学系,安徽 合肥 230032;
2. 马鞍山市疾病预防控制中心慢性病防治与健康管理科
Author(s):
ZHU Jin-liang* QIN Qi-rong LIU Meng-yu HE Jia-liu HU Ming-jun HUANG Fen
*Department of Epidemiology and Health Statistics, School of Public Health, Anhui Medical University, Hefei, Anhui 230032, China
关键词:
肺结节随访转归低剂量螺旋计算机断层扫描
Keywords:
Pulmonary nodule Follow-up Outcome Low-dose computed tomography
分类号:
R734R18
DOI:
10.20043/j.cnki.MPM.202201085
文献标识码:
A
摘要:
目的 了解马鞍山市肺癌筛查队列肺结节检出者的结节转归状况,并分析其影响因素。方法 对2020年基线筛查出的398名肺结节检出者于2021年进行随访调查,收集基线及随访期间的基本资料和结节信息,采用单因素分析结合多因素logistic回归分析探讨肺癌筛查人群肺结节转归的影响因素。结果 在这398人中,共有95人(23.9%)结节进展,64人(16.1%)结节改善,239人(60.0%)结节稳定。多因素logistic回归分析结果显示,进展组与稳定组相比,有肺部相关疾病史(OR = 2.920,95%CI:1.169~7.291,P = 0.022)及有职业暴露(OR = 1.656,95%CI:1.002~2.735,P = 0.049)者,更容易出现结节进展。改善组与稳定组相比,高中及以上学历(OR = 2.361,95%CI:1.036~5.383,P = 0.041)者更容易出现结节改善,没有油烟暴露(OR = 0.504,95%CI:0.281~0.904,P = 0.021)者更容易出现结节改善。结论 文化程度、肺部相关疾病史、职业暴露、油烟暴露等因素是影响肺结节转归的重要因素。
Abstract:
Objective To investigate the outcome of pulmonary nodules in Ma’anshan lung cancer screening cohort and analyze the risk factors. Methods In total 398 respondents with pulmonary nodules were screened at baseline in 2020 and followed up in 2021. Basic data and nodules information were collected during the baseline and follow-up period. Univariate analysis combined with multivariate logistic regression analysis was used to explore the factors influencing the outcome of pulmonary nodules in the lung cancer screening people. Results Among the 398 respondents, 95 (23.9%) had nodules progression, 64 (16.1%) had nodules improvement, and 239 (60.0%) had stable nodules. The results of multifactorial logistic regression analysis showed that those with a history of lung-related disease (OR=2.920, 95%CI: 1.169-7.291, P=0.022) and occupational exposure (OR=1.656, 95%CI: 1.002-2.735, P=0.049) were more likely to have nodule progression in the progression group compared with the stable group. Those with high school or higher education (OR=2.361, 95%CI: 1.036-5.383, P=0.041) and those without kitchen lampblack exposure (OR=0.504, 95%CI: 0.281-0.904, P=0.021) were more likely to show nodal improvement compared to the stable group. Conclusion Education level, history of lung-related diseases, occupational exposure, and kitchen lampblack exposure are important factors influencing the regression of pulmonary nodules.

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备注/Memo

备注/Memo:
基金项目:安徽省科技惠民示范工程(202007d07050008);安徽省卫生健康委科研项目(AHWJ2021a026)
作者简介:朱金亮(1993—),男,硕士在读,研究方向:肿瘤流行病学
通信作者:黄芬,E-mail: fenh@ahmu.edu.cn
更新日期/Last Update: 2022-07-28