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|本期目录/Table of Contents|

我国中老年人群骨关节炎罹患现状及其关联因素分析(PDF)

《现代预防医学》[ISSN:1003-8507/CN:51-1365/R]

期数:
2022年22期
页码:
4071-4076
栏目:
流行病与统计方法
出版日期:
2022-11-30

文章信息/Info

Title:
Analysis of associated factors of osteoarthritis in middle-aged and older population in China
作者:
周鑫茹吴雨浓田一然陈嘉怡蔡可心周欢
四川大学华西公共卫生学院/华西第四医院,四川 成都 610041
Author(s):
ZHOU Xin-ru WU Yu-nong TIAN Yi-ran CHEN Jia-yi CAI Ke-xin ZHOU Huan
West China School of Public Health/West China Fourth Hospital, Sichuan University, Chengdu, Sichuan 610041, China
关键词:
骨关节炎中老年人关联因素个体因素环境因素
Keywords:
Osteoarthritis Middle-aged and older Associated factors Individual factors Environmental factors
分类号:
R684.3
DOI:
10.20043/j.cnki.MPM.202204341
文献标识码:
A
摘要:
目的 了解我国中老年人群罹患骨关节炎现状及其关联因素。方法 采用2015年和2018年中国健康养老追踪调查(CHARLS)数据,纳入中老年人群(≥45岁)作为研究对象,运用χ2检验和多因素logistic回归分析中老年人群骨关节炎的关联因素。结果 纳入7 050名中老年人,骨关节炎患病率为33.69%。多因素logistic回归结果表明,从个体社会人口学特征看,年龄≥60岁(OR = 2.254,95%CI:1.985~2.558)、女性(OR = 1.353,95%CI:1.200~1.527)是骨关节炎的危险因素;从慢性病患病情况看,患有高血压(OR = 1.228,95%CI:1.072~1.408)、心脏病(OR = 1.607,95%CI:1.361~1.897)、中风(OR = 2.303,95%CI:1.604~3.306)、肾脏疾病(OR = 2.147,95%CI:1.744~2.644)、胃部疾病或消化系统疾病(OR = 2.810,95%CI:2.487~3.175)是骨关节炎的危险因素;从居住环境看,居住在城市地区(OR = 0.637,95%CI:0.541~0.750)、住房有电梯(OR = 0.879,95%CI:0.785~0.985)、坐式厕所(OR = 0.669,95%CI:0.580~0.770)是骨关节炎的保护因素。结论 我国中老年人群骨关节炎患病状况不容乐观,其关联因素是多方面的,应从个体层面到环境层面重视对骨关节炎的防控。
Abstract:
Objective To explore the current situation and the associated factors of osteoarthritis in middle-aged and older people in China. Methods Using the data of the middle-aged and older population above 45 years old in the China Health and Retirement Longitudinal Study (CHARLS) in 2015 and 2018, associated factors of osteoarthritis in middle-aged and older population were analyzed by χ2 test and Multivariate Logistic regression. Results A total of 7 050 participants were included in the study, and the prevalence rate of osteoarthritis was 33.69%. Regarding individual sociodemographic characteristics, age over 60 (OR=2.254, 95%CI: 1.985-2.558) and female (OR=1.353, 95%CI: 1.200-1.527) were risk factors for osteoarthritis. Regarding chronic disease comorbidities, other chronic diseases, including hypertension (OR=1.228, 95%CI: 1.072-1.408), heart disease (OR=1.607, 95%CI: 1.361-1.897), stroke (OR=2.303, 95%CI: 1.604-3.306), kidney disease (OR=2.147, 95%CI: 1.744-2.644), and stomach disease or digestive disease (OR=2.810, 95%CI: 2.487-3.175) were risk factors for osteoarthritis. Regarding living environment, living in the urban areas (OR=0.637, 95%CI: 0.541-0.750) and housing with elevator (OR=0.879, 95%CI: 0.785-0.985) and sitting toilet (OR=0.669, 95%CI: 0.580-0.770) were the protective factors of osteoarthritis. Conclusion The situation of osteoarthritis in middle-aged and elderly people is not optimistic. The related factors are many, and the prevention and control of osteoarthritis should be paid more attention to from the individual level to the environmental level.

参考文献/References

[ 1 ] 张莹莹,李旭东,杨佳娟,等.中国40岁及以上人群骨关节炎患病率的Meta分析[J].中国循证医学杂志,2021,21(4):407 - 414.Zhang YY, Li XD, Yang JJ, et al. The prevalence of osteoarthritis in Chinese aged 40 and over: a meta - analysis[J]. Chinese Journal of Evidence - Based Medicine, 2021, 21(4): 407 - 414.
[ 2 ] Long H, Zeng X, Liu Q, et al. Burden of osteoarthritis in China,1990 - 2017:findings from the Global Burden of Disease Study 2017[J]. The Lancet Rheumatology, 2020, 2(3): e164 - e172.
[ 3 ] 冯晓晴,蔡道章,余星磊,等.基于GBD大数据中国膝骨关节炎疾病负担现状与趋势分析[J].现代预防医学,2022,49(10):1753 - 1760.Feng XQ, Cai DZ, Yu XL, et al. Analysis of current situation and trend of disease burden of knee osteoarthritis in China based on GBD big data[J]. Modern Preventive Medicine, 2022, 49(10): 1753 - 1760.
[ 4 ] Zhang Z, Huang C, Jiang Q, et al. Guidelines for the diagnosis and treatment of osteoarthritis in China(2019 edition)[J]. Annals of Translational Medicine, 2020, 8(19): 1213.
[ 5 ] 许成燕,陈军香,王教明,等.中国人群膝骨关节炎危险因素的Meta分析[J].中国循证医学杂志,2021,21(7):772 - 778.Xu CY, Chen JX, Wang JM, et al. The risk factors for knee osteoarthritis among Chinese population: a meta - analysis[J]. Chinese Journal of Evidence - Based Medicine, 2021, 21(7): 772 - 778.
[ 6 ] Yc H, Li Z, Peter - G A, et al. Pathogenesis of osteoarthritis: risk factors, regulatory pathways in chondrocytes, and experimental models[J]. Biology, 2020, 9(8): 194.
[ 7 ] 黎丹东,李琳琳,苏峰,等.膝骨关节炎与性别和年龄的相关性研究[J].临床医学研究与实践,2019,4(31):1 - 3.Li DD, Li LL, Su F, et al. Study on the correlation between knee osteoarthritis and gender and age[J]. Clinical Research and Practice, 2019, 4(31): 1 - 3.
[ 8 ] 刘勇,吴雪,罗采南,等.新疆210例骨关节炎临床特点及危险因素分析[J].新疆医学,2021,51(11):1236 - 1238.Liu Y, Wu X, Luo CN, et al. Clinical characteristics and risk factors of 210 cases of osteoarthritis in Xinjiang[J]. Xinjiang Medicine, 2021, 51(11): 1236 - 1238.
[ 9 ] 赵昌,李红,胡志富,等.云南大理地区膝关节骨性关节炎危险因素分析[J].大理大学学报,2019,4(4):75 - 78.Zhao C, Li H, Hu ZF, et al. Analysis of risk factors for knee osteoarthritis in Dali area of Yunnan[J]. Journal of Dali University, 2019, 4(4): 75 - 78.
[ 10 ] Cindy - G B, Konstantinos H, Southam L, et al. Deciphering osteoarthritis genetics across 826,690 individuals from 9 populations[J]. Cell, 2021, 184(18): 4784 - 4818.
[ 11 ] 耿云航,李桂石,刘晓阳.骨关节炎发病易感基因及环境因素的现状研究[J].实用手外科杂志,2017,31(4):477 - 479.Geng YH, Li GD, Liu XY. Study on the susceptibility genes and environmental factors of osteoarthritis[J]. Journal of Practical Hand Surgery, 2017, 31(4): 477 - 479.
[ 12 ] 雷普超,吴洋洋,李玲玲,等.健康生态学视角下我国中老年慢性病患者抑郁的影响因素分析[J].现代预防医学,2021,48(7):1253 - 1258.Lei PC, Wu YY, Li LL, et al. The analysis of impact factors of depression among middle - aged and older chronic diseases patients in China based on health ecological aspect[J]. Modern Preventive Medicine, 2021, 48(7): 1253 - 1258.
[ 13 ] 中华人民共和国国家卫生和计划生育委员会.WS/T 428 - 2013 成人体重判定[S].北京:中国标准出版社,2013.National Health and Family Planning Commission, People’s Republic of China. WS/T 428 - 2013 Criteria of weight for adults[S]. Beijing: Standards Press of China, 2013.
[ 14 ] 孙双圆,郭雁飞,阮晔,等.50岁及以上人群生活质量与体力活动的关联研究[J].中华流行病学杂志,2019,40(10):1245 - 1251.Sun SY, Guo YF, Ruan Y, et al. Association between quality of Life and physical activity among People aged 50 years and over[J]. Chinese Journal of Epidemiology, 2019, 40(10): 1245 - 1251.
[ 15 ] 张东云译,Jacob L.骨关节炎和脑卒中发病率的相关性[J].中国康复,2021,36(9):1.Zhang DY, Jacob L. Jacob L. Correlation between osteoarthritis and stroke incidence[J]. Rehabilitation in China, 2021, 36(9): 1.
[ 16 ] 刘冰洁.基于零膨胀计数模型的骨关节炎危险因素分析及健康管理策略研究[D].太原:山西医科大学,2021.Liu BJ. Analysis of risk factors and health management strategies of osteoarthritis based on zero expansion counting model[D]. Taiyuan: Shanxi Medical University, 2021.
[ 17 ] 文晨曦,李敬扬,文振华.骨关节炎与衰老相关的发病机制[J].医学综述,2022,28(10):1911 - 1916.Wen CX, Li JY, Wen ZH. The pathogenesis of osteoarthritis and aging[J]. Medical Review, 2022, 28(10): 1911 - 1916.
[ 18 ] 于波,彭伟秋,李富明.导致膝关节骨性关节炎的常见危险因素[J].系统医学,2018,3(7):194 - 198.Yu B, Peng WQ, Li FM. Common risk factors for knee osteoarthritis[J]. Systems Medicine, 2018, 3(7): 194 - 198.
[ 19 ] 牟利民,张文豪,陈万吉,等.雌激素及雌激素受体与骨关节炎的相关性研究进展[J].浙江医学,2021,43(24):2721 - 2724.Mou LM, Zhang WH, Chen WJ, et al. Research progress on the relationship between estrogen,estrogen receptor and osteoarthritis[J]. Zhejiang Medicine, 2021, 43(24): 2721 - 2724.
[ 20 ] 王海珠.四川省多山地区中老年人膝关节骨性关节炎的流行病学调查研究[J].中国老年保健医学,2021,19(3):80 - 84.Wang HZ. Epidemiological investigation of knee osteoarthritis in middle - aged and elderly in mountainous areas of Sichuan Province[J]. Chinese Geriatric Medicine, 2021, 19(3): 80 - 84.
[ 21 ] Grotle M, Hagen KB, Natvig B, et al. Obesity and osteoarthritis in knee, hip and/or hand: An epidemiological study in the general population with 10 years follow - up[J]. BMC Musculoskeletal Disorders, 2008, 9(1): 132.
[ 22 ] Chloe G, Guiguet - Auclair C, Mourgues C, et al. Physical activity level and association with behavioral factors in knee osteoarthritis[J]. Annals of Physical and Rehabilitation Medicine, 2019, 62(1): 14 - 20.
[ 23 ] Fernández - Torres J, Zamudio - Cuevas Y, Martínez - Nava GA, et al. Impact of Cadmium mediated by tobacco use in musculoskeletal diseases[J]. Biological Trace Element Research, 2022, 200(5): 2008 - 2015.
[ 24 ] 陈泓伯,吴俊慧,武轶群,等.2015 - 2017年北京市成年骨关节炎患者主要合并症的流行病学研究[J].第三军医大学学报,2021,43(12):1103 - 1108.Chen HB, Wu JH, Wu YQ, et al. Epidemiology of major comorbidities in adult patients with osteoarthritis in Beijing from 2015 to 2017[J]. Journal of Third Military Medical University, 2021, 43(12): 1103 - 1108.
[ 25 ] Xie Y, Zhou W, Zhong Z, et al. Metabolic syndrome, hypertension, and hyperglycemia were positively associated with knee osteoarthritis, while dyslipidemia showed no association with knee osteoarthritis[J]. Clinical Rheumatology, 2021, 40(2): 711 - 724.
[ 26 ] Ching K, Houard X, Berenbaum F, et al. Hypertension meets osteoarthritis - revisiting the vascular aetiology hypothesis[J]. Nature Reviews Rheumatology, 2021, 17(9): 533 - 549.
[ 27 ] Liu SY, Zhu WT, Chen BW, et al. Bidirectional association between metabolic syndrome and osteoarthritis: a meta - analysis of observational studies[J]. Diabetology & Metabolic Syndrome, 2020, 12(1): 38.
[ 28 ] 麦少君.止痛药与关节炎患者出现较高的心脏病风险相关 [J].心血管病防治知识:科普版,2019,(34):48.Mai SJ. Are painkillers associated with a higher risk of heart disease in patients with arthritis [J]. Knowledge of Prevention and Treatment of Cardiovascular Diseases: Popular Science Edition, 2019, (34): 48.
[ 29 ] 白淑红,李洛丽.2013 - 2015年某农村地区骨关节炎患病相关影响因素[J].江苏预防医学,2018,29(2):2.Bai SH, Li LL. Related factors of osteoarthritis in a rural area from 2013 to 2015[J]. Jiangsu Preventive Medicine, 2018, 29(2): 2.

备注/Memo

备注/Memo:
作者简介:周鑫茹(2000—),女,本科在读,研究方向:公共卫生与预防医学
通信作者:周欢,E-mail: zhouhuan@scu.edu.cn
更新日期/Last Update: 2022-11-30